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Wall Street Journal: Drug Makers Tiptoe Back Into Antibiotic R&D

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23.01.14

The spread of superbugs is a dire health emergency, but until recently the economics and regulatory hurdles were pushing many drug companies away from the search for new antibiotics. Full Article

Genetic Engineering and Biology News: Biopharmas Drive Antibiotic Development

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14.08.13

At a time when the need for antibiotics is high, pharmaceutical companies are abandoning antibiotics development in favor of larger, more predictable markets.  That has been the situation for the past few years, and it isn’t changing, according to Aaron S. Kesselheim, M.D., J.D., associate physician at Brigham and Women’s Hospital, and assistant professor of medicine at Harvard Medical School. Yet, with the incidence of antibiotic resistance growing, there is an acute need for new, more effective targets. Full Article

Futurity: ‘SIDE-KICK’ DRUGS COULD IMPROVE ANTIBIOTICS

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18.01.13

A new technique designed to make current antibiotics more effective works by disabling select genes in bacteria.  Described in the journal Nature Biotechnology, the technique systematically identifies genes within E. coli bacteria that inhibit the production of molecules called reactive oxygen species (ROS) that damage the bacteria’s DNA.  Full Article